Guidelines for Carotid Endarterectomy
- 1 January 1995
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Stroke
- Vol. 26 (1), 188-201
- https://doi.org/10.1161/01.str.26.1.188
Abstract
Background and Purpose Indications for carotid endarterectomy have engendered considerable debate among experts and have resulted in publication of retrospective reviews, natural history studies, audits of community practice, position papers, expert opinion statements, and finally prospective randomized trials. The American Heart Association assembled a group of experts in a multidisciplinary consensus conference to develop this statement. Methods A conference was held July 16-18, 1993, in Park City, Utah, that included recognized experts in neurology, neurosurgery, vascular surgery, and healthcare planning. A program of critical topics was developed, and each expert presented a talk and provided the chairman with a summary statement. From these summary statements a document was developed and edited onsite to achieve consensus before final revision. Results The first section of this document reviews the natural history, methods of patient evaluation, options for medical management, results of surgical management, data from position statements, and results to date of prospective randomized trials for symptomatic and asymptomatic patients with carotid artery disease. The second section divides 96 potential indications for carotid endarterectomy, based on surgical risk, into four categories: (1) Proven: This is the strongest indication for carotid endarterectomy; data are supported by results of prospective contemporary randomized trials. (2) Acceptable but not proven: a good indication for operation; supported by promising but not scientifically certain data. (3) Uncertain: Data are insufficient to define the risk/benefit ratio. (4) Proven inappropriate: Current data are adequate to show that the risk of surgery outweighs any benefit. Conclusions Indications for carotid endarterectomy in symptomatic good-risk patients with a surgeon whose surgical morbidity and mortality rate is less than 6% are as follows. (1) Proven : one or more TIAs in the past 6 months and carotid stenosis ≥ 70% or mild stroke within 6 months and a carotid stenosis ≥ 70%; (2) acceptable but not proven : TIAs within the past 6 months and a stenosis 50% to 69%, progressive stroke and a stenosis ≥ 70%, mild or moderate stroke in the past 6 months and a stenosis 50% to 69%, or carotid endarterectomy ipsilateral to TIAs and a stenosis ≥ 70% combined with required coronary artery bypass grafting; (3) uncertain : TIAs with a stenosis proven inappropriate: moderate stroke with stenosis uncertain : stenosis >75% in a high-risk patient/surgeon (surgical morbidity and mortality rate >3%), combined carotid/coronary operations, or ulcerative lesions without hemodynamically significant stenosis; (4) proven inappropriate : operations with a combined stroke morbidity and mortality >5%.Keywords
This publication has 133 references indexed in Scilit:
- Efficacy of Carotid Endarterectomy for Asymptomatic Carotid StenosisNew England Journal of Medicine, 1993
- MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosisThe Lancet, 1991
- Effect of Intraoperative Intervention on Neurological Outcome Based on Electroencephalographs Monitoring During Cardiopulmonary BypassThe Annals of Thoracic Surgery, 1989
- A Randomized Trial Comparing Ticlopidine Hydrochloride with Aspirin for the Prevention of Stroke in High-Risk PatientsNew England Journal of Medicine, 1989
- THE CANADIAN AMERICAN TICLOPIDINE STUDY (CATS) IN THROMBOEMBOLIC STROKEThe Lancet, 1989
- Outcome in Patients with Asymptomatic Neck BruitsNew England Journal of Medicine, 1986
- Risk of Stroke in Asymptomatic Persons with Cervical Arterial BruitsNew England Journal of Medicine, 1980
- Diagnosis of Carotid Artery StenosisAnnals of Surgery, 1980
- Asymptomatic Carotid BruitAnnals of Surgery, 1978
- Carotid Endarterectomy for Cerebrovascular InsufficiencyAnnals of Surgery, 1970