Phylogeny of the Simbu serogroup of the genus Bunyavirus
Open Access
- 1 September 2001
- journal article
- Published by Microbiology Society in Journal of General Virology
- Vol. 82 (9), 2173-2181
- https://doi.org/10.1099/0022-1317-82-9-2173
Abstract
The Simbu serogroup of the genus Bunyavirus, family Bunyaviridae contains 25 viruses. Previous serological studies provided important information regarding some but not all of the relationships among Simbu serogroup viruses. This report describes the nucleotide sequence determination of the nucleocapsid (N) gene of the small genomic segment of 14 Simbu serogroup viruses and partial nucleotide sequence determination of the G2 glycoprotein-coding region (encoded by the medium RNA segment) of 19 viruses. The overall phylogeny of the Simbu serogroup inferred from analyses of the N gene was similar to that inferred from analyses of the G2 protein-coding region. Both analyses revealed that the Simbu serogroup viruses have evolved into at least five major phylogenetic lineages. In general, these phylogenetic lineages were consistent with the previous serological data, but provided a more detailed understanding of the relatedness amongst many viruses. In comparison to previous phylogenetic studies on the California and Bunyamwera serogroups of the Bunyavirus genus, the Simbu serogroup displays much larger genetic variation in the N gene (up to 40% amino acid sequence divergence).Keywords
This publication has 25 references indexed in Scilit:
- The S RNA genomic sequences of Inkoo, San Angelo, Serra do Navio, South River and Tahyna bunyavirusesJournal of General Virology, 1996
- Determination and comparative analysis of the small RNA genomic sequences of California encephalitis, Jamestown Canyon, Jerry Slough, Melao, Keystone and Trivittatus viruses (Bunyaviridae, genus Bunyavirus, California serogroup)Journal of General Virology, 1995
- Nucleotide and deduced amino acid sequence of the structural protein genes of Japanese encephalitis viruses from different geographical locationsJournal of General Virology, 1995
- The S RNA genome segments of Batai, Cache Valley, Guaroa, Kairi, Lumbo, Main Drain and Northway bunyaviruses: sequence determination and analysisJournal of General Virology, 1994
- Organization of Germiston bunyavirus M open reading frame and physicochemical properties of the envelope glycoproteinsJournal of General Virology, 1992
- Mutagenesis of the L protein encoded by Bunyamwera virus and production of monospecific antibodiesJournal of General Virology, 1992
- Nucleotide Sequence Analysis of the Small (S) RNA Segment of Bunyamwera Virus, the Prototype of the Family BunyaviridaeJournal of General Virology, 1989
- Organization of the middle RNA segment of snowshoe hare bunyavirusVirology, 1988
- Localized conserved regions of the S RNA gene products of bunyaviruses are revealed by sequence analyses of the Simbu serogroup Aino virusVirus Research, 1984
- A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequencesJournal of Molecular Evolution, 1980