Analytik von Gangliosiden unter besonderer Berücksichtigung der Milch
- 1 February 1988
- journal article
- abstracts
- Published by Springer Science and Business Media LLC in Zeitschrift für Lebensmittel-Untersuchung und Forschung
- Vol. 186 (2), 99-107
- https://doi.org/10.1007/bf01042701
Abstract
Gangliosides are sialic acid containing lipid compounds of a very complex nature, which are involved in many physiological processes. Gangliosides are very important constituents of membrane material in animal tissue, where they occur at very low concentrations. Improved analytical procedures are therefore required to study their behaviour, their role in living systems and their isolation for further investigations. In this paper, all analytical methods which may be important in the analysis of gangliosides are summarized and discussed. These include extraction, purification, enrichment and chromatographic procedures. In bovine milk, three gangliosides of known structure are present. Their isolation, structure and analytical importance (buttermilk) are also reported. Ganglioside sind Sialinsäure enthaltende Lipide (N-Acetylneuraminsäure), die als funktionell wichtige Bausteine besonders in Membranen anzutreffen sind. Sie spielen eine wichtige Rolle in vielen elementaren physiologischen Vorgängen in tierischem Gewebe. Um ihre weite Bedeutung näher zu untersuchen bzw. die komplexe Struktur zu charakterisieren, sind aufwendige analytische Verfahren notwendig, die in dieser kurzen Übersicht dargestellt werden, d. h. Extraktion, Reinigung und Anreicherung Bowie chromatographische Methoden. In der Milch (Milchfettkügelchenmembran) wurden bisher drei Ganglioside in ihrer Struktur aufgeklärt. Sie werden bei der Verbutterung in der Buttermilch angereichert und könnten so als wichtiges analytisches Hilfsmittel dienen.Keywords
This publication has 56 references indexed in Scilit:
- Characterization of two molecular species GD3 ganglioside from bovine buttermilkBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1985
- GangliosidesPublished by Elsevier BV ,1985
- Proteins mask gangliosides in milk fat globule and erythrocyte membranesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1976
- Composition and synthesis of gangliosides in mammary gland and milk of the bovineBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1974
- A new procedure for the extraction, purification and fractionation of brain gangliosidesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1973
- THE PATTERN OF MAMMALIAN BRAIN GANGLIOSIDES‐II EVALUATION OF THE EXTRACTION PROCEDURES, POSTMORTEM CHANGES AND THE EFFECT OF FORMALIN PRESERVATION*Journal of Neurochemistry, 1965
- The gangliosidesJournal of Lipid Research, 1964
- On the isolation and characterization of gangliosidesBiochimica et Biophysica Acta, 1962
- Quantitive estimation of sialic acids: II. A colorimetric resorcinol-hydrochloric acid methodBiochimica et Biophysica Acta, 1957
- Über die Ganglioside, eine neue Gruppe von zuckerhaltigen GehirnlipoidenHoppe-Seyler´s Zeitschrift für physiologische Chemie, 1942