Combining geometric morphometrics and functional simulation: an emerging toolkit for virtual functional analyses
- 29 September 2010
- journal article
- review article
- Published by Wiley in Journal of Anatomy
- Vol. 218 (1), 3-15
- https://doi.org/10.1111/j.1469-7580.2010.01301.x
Abstract
The development of virtual methods for anatomical reconstruction and functional simulation of skeletal structures offers great promise in evolutionary and ontogenetic investigations of form-function relationships. Key developments reviewed here include geometric morphometric methods for the analysis and visualization of variations in form (size and shape), finite element methods for the prediction of mechanical performance of skeletal structures under load and multibody dynamics methods for the simulation and prediction of musculoskeletal function. These techniques are all used in studies of form and function in biology, but only recently have they been combined in novel ways to facilitate biomechanical modelling that takes account of variations in form, can statistically compare performance, and relate performance to form and its covariates. Here we provide several examples that illustrate how these approaches can be combined and we highlight areas that require further investigation and development before we can claim a mature theory and toolkit for a statistical biomechanical framework that unites these methods.This publication has 75 references indexed in Scilit:
- The mechanical function of the periodontal ligament in the macaque mandible: a validation and sensitivity study using finite element analysisJournal of Anatomy, 2010
- In vivo bone strain and finite-element modeling of the craniofacial haft in catarrhine primatesJournal of Anatomy, 2010
- Morphing methods to parameterize specimen-specific finite element model geometriesJournal of Biomechanics, 2010
- Predicting muscle activation patterns from motion and anatomy: modelling the skull ofSphenodon(Diapsida: Rhynchocephalia)Journal of The Royal Society Interface, 2009
- Biomechanical assessment of evolutionary changes in the lepidosaurian skullProceedings of the National Academy of Sciences of the United States of America, 2009
- The feeding biomechanics and dietary ecology of Australopithecus africanusProceedings of the National Academy of Sciences of the United States of America, 2009
- Combined finite element and multibody dynamics analysis of biting in a Uromastyx hardwickii lizard skullJournal of Anatomy, 2008
- Assessing mechanical function of the zygomatic region in macaques: validation and sensitivity testing of finite element modelsJournal of Anatomy, 2006
- Dynamic mechanics in the pig mandibular symphysisJournal of Anatomy, 2006
- “Stresscoat” deformation studies of the femur under static vertical loadingThe Anatomical Record, 1948