Exposure to air pollution is associated with adverse cardiopulmonary health effects in international travellers
- 6 May 2019
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Travel Medicine
- Vol. 26 (5)
- https://doi.org/10.1093/jtm/taz032
Abstract
Background: With the number of annual global travellers reaching 1.2 billion, many individuals encounter greater levels of air pollution when they travel abroad to megacities around the world. This study's objective was to determine if visits to cities abroad with greater levels of air pollution adversely impact cardiopulmonary health. Methods: A total of 34 non-smoking healthy adult participants who travelled abroad to selected cities from the New York City (NYC) metropolitan area were pre-trained to measure lung function, blood pressure and heart rate (HR)/HR variability (HRV) and record symptoms before, during and after travelling abroad. Outdoor particulate matter (PM)(2.5) concentrations were obtained from central monitors in each city. Associations between PM exposure concentrations and cardiopulmonary health endpoints were analysed using a mixed effects statistical design. Results: East and South Asian cities had significantly higher PM2.5 concentrations compared with pre-travel NYC PM2.5 levels, with maximum concentrations reaching 503 mu g/m(3). PMexposure-related associations for lung function were statistically significant and strongest between evening Forced Expiratory Volume in the first second (FEV1) and same-day morning PM2.5 concentrations; a 10-mu g/m(3) increase in outdoor PM2.5 was associated with a mean decrease of 7 mL. Travel to a highly polluted city (PM2.5 > 100 mu g/m(3)) was associated with a 209-ml reduction in evening FEV1 compared with a low polluted city (PM2.5 < 35 mu g/m(3)). In general, participants who travelled to East and South Asian cities experienced increased respiratory symptoms/scores and changes in HR and HRV. Conclusions: Exposure to increased levels of PM2.5 in cities abroad caused small but statistically significant acute changes in cardiopulmonary function and respiratory symptoms in healthy young adults. These data suggest that travel-related exposure to increased PM2.5 adversely impacts cardiopulmonary health, which may be particularly important for travellers with pre-existing respiratory or cardiac disease.Keywords
Funding Information
- National Institute of Environmental Health Sciences (ES000260, ES007324)
- Air and Waste Management Association Scholarship 2017
- New York University College of Global Public Health
This publication has 37 references indexed in Scilit:
- Personal Exposures to Traffic-Related Air Pollution and Acute Respiratory Health among Bronx Schoolchildren with AsthmaEnvironmental Health Perspectives, 2011
- Human health risks in megacities due to air pollutionAtmospheric Environment, 2010
- Measurement of inflammation and oxidative stress following drastic changes in air pollution during the Beijing Olympics: a panel study approachAnnals of the New York Academy of Sciences, 2010
- Association of Heart Rate Variability in Taxi Drivers with Marked Changes in Particulate Air Pollution in Beijing in 2008Environmental Health Perspectives, 2010
- Associations between Recent Exposure to Ambient Fine Particulate Matter and Blood Pressure in the Multi-Ethnic Study of Atherosclerosis (MESA)Environmental Health Perspectives, 2008
- Comparison between peak expiratory flow and FEV1 measurements on a home spirometer and on a pneumotachograph in children with asthmaPediatric Pulmonology, 2007
- A Comparison of Studies on the Effects of Controlled Exposure to Fine, Coarse and Ultrafine Ambient Particulate Matter from a Single LocationInhalation Toxicology, 2007
- Standardisation of spirometryEuropean Respiratory Journal, 2005
- Elderly humans exposed to concentrated air pollution particles have decreased heart rate variabilityEuropean Respiratory Journal, 2003
- Measurements of sulfur dioxide, ozone and ammonia concentrations in Asia, Africa, and South America using passive samplersAtmospheric Environment, 2003