Over the Counter Availability of Antituberculosis Drugs in Tbilisi, Georgia in the Setting of a High Prevalence of MDR-TB
Open Access
- 1 January 2009
- journal article
- research article
- Published by Hindawi Limited in Interdisciplinary Perspectives on Infectious Diseases
- Vol. 2009, 1-3
- https://doi.org/10.1155/2009/513609
Abstract
Georgia, a country of 4.5 million people, has a high incidence of tuberculosis (TB) including drug resistant cases. Easy access and inappropriate use of anti-TB drugs are risk factors for further development of multidrug resistant (MDR)-TB. We carried out an investigation to assess the availability of over the counter anti-TB agents in pharmacies in Tbilisi. During February 2006, 15 pharmacies were randomly selected and the pharmacist at each store was interviewed. We found that all anti-TB medications stocked by these pharmacies were available and sold without a prescription. All 15 pharmacies sold isoniazid, rifampicin, and streptomycin; 13 (87%) of 15 pharmacies also sold pyrazinamide, ethambutol. Second line anti-TB drugs such as amikacin and kanamycin (injectable agents) and older fluoroquinolones (ofloxacin and ciprofloxacin) were available at 13 pharmacies while newer generation fluoroquinolones were less available(3 sold leovofloxacin, none sold moxifloxacin). The ease access and availability of anti-TB agents is of a great concern given the high prevalence of TB including MDR-TB in Georgia. The potential for misuse of these anti-TB drugs can lead to the development of further drug resistance. These drugs should only be available by prescription in order to reduce the chance of amplifying drug resistance.Keywords
Funding Information
- Fogarty International Center (D43 TW007124, D43 TW01042)
This publication has 10 references indexed in Scilit:
- Prevalence and risk factors for multidrug-resistant tuberculosis in the Republic of Georgia: a population-based study.2009
- TuberculosisThe Lancet, 2007
- Epidemiology of antituberculosis drug resistance (the Global Project on Anti-tuberculosis Drug Resistance Surveillance): an updated analysisThe Lancet, 2006
- Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South AfricaThe Lancet, 2006
- INCIDENCE OF POLARIZING FOREIGN BODIES IN LUNG BIOPSIES OF PATIENTS WITH PULMONARY SARCOIDOSISChest, 2006
- Faculty Opinions recommendation of Emergence of Mycobacterium tuberculosis with extensive resistance to second-line drugs--worldwide, 2000-2004.Published by H1 Connect ,2006
- Tuberculosis control and the private health sector in Bolivia: a survey of pharmacies2004
- Control of tuberculosis in an urban setting in Nepal: public-private partnership.2004
- Private pharmacies in tuberculosis control--a neglected link.2002
- Private pharmacies and tuberculosis control: a survey of case detection skills and reported anti-tuberculosis drug dispensing in private pharmacies in Ho Chi Minh City, Vietnam.2000