Inflammatory Bowel Disease: A Canadian Burden of Illness Review
Top Cited Papers
Open Access
- 1 January 2012
- journal article
- review article
- Published by Hindawi Limited in Canadian Journal of Gastroenterology
- Vol. 26 (11), 811-817
- https://doi.org/10.1155/2012/984575
Abstract
BACKGROUND: Inflammatory bowel diseases (IBD) – Crohn’s disease (CD) and ulcerative colitis (UC) – significantly impact quality of life and account for substantial costs to the health care system and society.OBJECTIVE: To conduct a comprehensive review and summary of the burden of IBD that encompasses the epidemiology, direct medical costs, indirect costs and humanistic impact of these diseases in Canada.METHODS: A literature search focused on Canadian data sources. Analyses were applied to the current 2012 Canadian population.RESULTS: There are approximately 233,000 Canadians living with IBD in 2012 (129,000 individuals with CD and 104,000 with UC), corresponding to a prevalence of 0.67%. Approximately 10,200 incident cases occur annually. IBD can be diagnosed at any age, with typical onset occurring in the second or third decade of life. There are approximately 5900 Canadian children CONCLUSIONS: The present review documents a high burden of illness from IBD due to its high prevalence in Canada combined with high per-patient costs. Canada has among the highest prevalence and incidence rates of IBD in the world. Individuals with IBD face challenges in the current environment including lack of awareness of IBD as a chronic disease, late or inappropriate diagnosis, inequitable access to health care services and expensive medications, diminished employment prospects and limited community-based support.Keywords
This publication has 42 references indexed in Scilit:
- Outcomes of Pediatric Inflammatory Bowel Disease: Socioeconomic Status Disparity in a Universal-Access Healthcare SystemThe Journal of Pediatrics, 2011
- Epidemiology of pediatric inflammatory bowel disease: A systematic review of international trendsInflammatory Bowel Diseases, 2011
- Increasing incidence of paediatric inflammatory bowel disease in Ontario, Canada: evidence from health administrative dataGut, 2009
- Epidemiology of Crohnʼs Disease in QuéBec, CanadaInflammatory Bowel Diseases, 2009
- Longitudinal study of quality of life and psychological functioning for active, fluctuating, and inactive disease patterns in inflammatory bowel diseaseInflammatory Bowel Diseases, 2008
- Health-related quality of life in inflammatory bowel disease patients: The role of psychopathology and personalityInflammatory Bowel Diseases, 2008
- Mortality by Medication Use Among Patients With Inflammatory Bowel Disease, 1996–2003Gastroenterology, 2007
- Certolizumab pegol, a monthly subcutaneously administered Fc-free anti-TNFα, improves health-related quality of life in patients with moderate to severe Crohn’s diseaseInternational Journal of Colorectal Disease, 2007
- Utilization of Health-Care Resources by Patients With IBD in Manitoba: A Profile of Time Since DiagnosisThe American Journal of Gastroenterology, 2007
- Mapping from Disease-Specific Measures to Utility: An Analysis of the Relationships between the Inflammatory Bowel Disease Questionnaire and Crohn's Disease Activity Index in Crohn's Disease and Measures of UtilityValue in Health, 2007