A Novel Sesterterpenoid, Nitiol, as a Potent Enhancer of IL-2 Gene Expression in a Human T Cell Line, from the Peruvian Folk Medicine "Hercumpuri" (Gentianella nitida).

Abstract

A novel sesterterpenoid designated as nitiol (1), possessing enhancement activity of IL-2 gene expression in a human T cell line, was isolated from the Peruvian folk medicine "Hercampuri" (Gentianella nitida). The structure was elucidated by extensive spectroscopic investigation.