Rupatadine for the treatment of allergic rhinitis and urticaria
- 10 January 2011
- journal article
- review article
- Published by Taylor & Francis Ltd in Expert Review of Clinical Immunology
- Vol. 7 (1), 15-20
- https://doi.org/10.1586/eci.10.85
Abstract
Allergies are a widespread group of diseases of civilization and most patients are still undertreated. Since histamine is considered to be the most important mediator in allergies such as allergic rhinitis and urticaria, the most commonly used drugs to treat these disorders are antihistamines acting on the histamine 1 (H1) receptor. The currently available antihistamines, however, have significant differences in their effects and safety profiles. Furthermore, the Allergic Rhinitis and its Impact on Asthma initiative calls for additional desirable properties of antihistamines. Here, we review the profile of rupatadine, a new dual platelet-activating factor and H1-receptor antagonist that fulfils these criteria and therefore offers an excellent option for the treatment of allergic diseases.Keywords
This publication has 39 references indexed in Scilit:
- Epidemiology of urticaria: a representative cross-sectional population surveyClinical and Experimental Dermatology, 2010
- Effects of a pseudoallergen‐free diet on chronic spontaneous urticaria: a prospective trialAllergy, 2009
- EAACI/GA²LEN/EDF/WAO guideline: management of urticariaAllergy, 2009
- GA2LEN (Global Allergy and Asthma European Network) addresses the allergy and asthma ‘epidemic’Allergy, 2009
- The German version of the chronic urticaria quality‐of‐life questionnaire: factor analysis, validation, and initial clinical findingsAllergy, 2009
- Frequency and clinical implications of skin autoreactivity to serum versus plasma in patients with chronic urticariaJournal of Allergy and Clinical Immunology, 2009
- Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*Allergy, 2008
- Quality of life in patients with chronic urticaria is differentially impaired and determined by psychiatric comorbidityBritish Journal of Dermatology, 2005
- Chronic idiopathic urticariaCurrent Opinion in Allergy and Clinical Immunology, 2003
- Allergic Rhinitis and Its Impact on AsthmaJournal of Allergy and Clinical Immunology, 2001