Increased frequency of the apolipoprotein E‐4 isoform in male subjects with multifactorial hypercholesterolemia
- 1 May 1985
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 27 (5), 458-462
- https://doi.org/10.1111/j.1399-0004.1985.tb00231.x
Abstract
The apoE polymorphism was studied by two-dimensional gel electrophoresis in serum samples from 62 male subjects with multifactorial hypercholesterolemia and from 63 normal subjects. The apoE-4 isoform was significantly more frequent (p less than 0.02) among the hypercholesterolemic subjects than among the normocholesterolemic controls.Keywords
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