End‐to‐End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation
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Open Access
- 2 October 2013
- journal article
- research article
- Published by Wiley in Angewandte Chemie
- Vol. 52 (47), 12359-12363
- https://doi.org/10.1002/anie.201305429
Abstract
A series of tubes: The continuous manufacture of a finished drug product starting from chemical intermediates is reported. The continuous pilot-scale plant used a novel route that incorporated many advantages of continuous-flow processes to produce active pharmaceutical ingredients and the drug product in one integrated system.Keywords
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