The effect of Camellia Sinensis (green tea) mouthwash on plaque-induced gingivitis: a single-blinded randomized controlled clinical trial
Open Access
- 24 September 2012
- journal article
- Published by Springer Science and Business Media LLC in DARU Journal of Pharmaceutical Sciences
- Vol. 20 (1), 39
- https://doi.org/10.1186/2008-2231-20-39
Abstract
Abstract Background and the purpose of the Study Complementary medicine received high attention during last decades. We aimed to assess the efficacy of Green tea mouthwash on plaque-induced gingivitis as the most common form of periodontal disease. Methods and materials We designed a single blinded placebo controlled clinical trial. High school female students with chronic generalized plaque-induced gingivitis were distributed to receive either 5 ml of Green tea 5% two times/day or normal saline with the same dosage. Gingival index (Sillness & Loe), plaque index (Sillness & Loe) and bleeding index (Barnett) were recorded at baseline and five consecutive weeks. Comparisons were made by a general linear model, repeated measure ANOVA and a Bonferroni test applied for multiple comparisons. Results Twenty five students were recruited in each arm of the study. A significant improvement was observed in all periodontal indices during the study (P < 0.001). Two groups were contrasted by changing patterns of alteration of indices (P < 0.05). Although total amount of improvement was higher in mouthwash group, the differences did not reach a statistically significant level (P > 0.05, observed power for GI: 0.09, PI: 0.11 and BI: 0.07). Conclusion Green tea mouthwash may be a safe and feasible adjunct treatment for inflammatory periodontal diseases. A future larger scale study is warranted for better evaluating the effect of green tea.Keywords
This publication has 21 references indexed in Scilit:
- A clinical, microbiological and immunological comparison between subgingival irrigation with Dentol™ and chlorhexidine in advanced periodontitisVideosurgery and Other Miniinvasive Techniques, 2011
- Effect of green tea catechin, a local drug delivery system as an adjunct to scaling and root planing in chronic periodontitis patients: A clinicomicrobiological studyJournal of Indian Society of Periodontology, 2011
- Tea polyphenols inhibit IL‐6 production in tumor necrosis factor superfamily 14‐stimulated human gingival fibroblastsMolecular Nutrition & Food Research, 2010
- Bruikbaarheid micronutriënten bij behandeling van parodontitisNederlands Tijdschrift Voor Tandheelkunde, 2010
- Relationship Between Intake of Green Tea and Periodontal DiseaseThe Journal of Periodontology, 2009
- Green tea may inhibit warfarinInternational Journal of Cardiology, 2007
- Efficacy of Subgingival Irrigation Using Herbal Extracts on Gingival InflammationThe Journal of Periodontology, 2003
- Inhibitory Effect of Tea Catechins on Collagenase ActivityThe Journal of Periodontology, 1993
- Anticaries Effects of Polyphenolic Compounds from Japanese Green TeaCaries Research, 1991
- Periodontal Disease in Pregnancy II. Correlation Between Oral Hygiene and Periodontal ConditionActa Odontologica Scandinavica, 1964