Effect of Treatment with Stimulant Medication on Nonverbal Executive Function and Visuomotor Speed in Children with Attention Deficit/Hyperactivity Disorder (ADHD)
- 30 April 2008
- journal article
- research article
- Published by Taylor & Francis Ltd in Child Neuropsychology
- Vol. 14 (3), 211-226
- https://doi.org/10.1080/09297040701220005
Abstract
This study used a novel hidden maze learning test to examine the nature and magnitude of impairment on separable aspects of executive function in 36 children with ADHD. A within-subject analysis of children with ADHD was also conducted to assess cognitive effects of open-label stimulant treatment. Compared to 31 age-matched controls, unmedicated children with ADHD were slower and made significantly more errors that were indicative of relative impairment in prepotent response inhibition and ability to “maintain set” while using simple rules to complete the task. Open-label administration of stimulant medication led to faster and more efficient performance, with children with ADHD making fewer perseverative and rule-break errors than when off medication. This instrument might be useful in monitoring treatment response in specific aspects of executive function and in assisting with dose-titration decisions.Keywords
This publication has 36 references indexed in Scilit:
- Practice Effects Associated with the Repeated Assessment of Cognitive Function Using the CogState Battery at 10-minute, One Week and One Month Test-retest IntervalsJournal of Clinical and Experimental Neuropsychology, 2006
- Characterizing cognition in ADHD: beyond executive dysfunctionTrends in Cognitive Sciences, 2006
- An investigation of visuospatial memory impairment in children with attention deficit hyperactivity disorder (ADHD), combined typePsychological Medicine, 2005
- Attention-deficit hyperactivity disorderThe Lancet, 2005
- Meta-Analysis of Intellectual and Neuropsychological Test Performance in Attention-Deficit/Hyperactivity Disorder.Neuropsychology, 2004
- Methylphenidate Improves Visual-Spatial Memory in Children With Attention-Deficit/Hyperactivity DisorderJournal of the American Academy of Child & Adolescent Psychiatry, 2004
- The effects of practice on the cognitive test performance of neurologically normal individuals assessed at brief test–retest intervalsJournal of the International Neuropsychological Society, 2003
- Contextual abnormalities of saccadic inhibition in children with attention deficit hyperactivity disorderExperimental Brain Research, 2001
- Meta-analysis of experiments with matched groups or repeated measures designs.Psychological Methods, 1996
- The Stepping-Stone Maze: A Directly Visible Space-Problem ApparatusThe Journal of General Psychology, 1931