Thromboembolic Complications with the Cloth-Covered Starr-Edwards Aortic Prosthesis in Patients Not Receiving Anticoagulants
- 30 June 1977
- journal article
- Published by Elsevier BV in The Annals of Thoracic Surgery
- Vol. 23 (6), 529-533
- https://doi.org/10.1016/s0003-4975(10)63696-x
Abstract
A comparison of the incidence of thromboembolic (TE) episodes was made in three groups of patient who underwent aortic valve replacement with the cloth-covered Starr-Edwards prostheses. Group 1 consisted of patients who received anticoagulants for either the entire period of follow-up or for a period of variable duration, after which these agents were no longer administered. When anticoagulants were stopped, 22 patients were categorized as Group 3 for study. Group 2 comprised patients who never received anticoagulants. Of the 147 patients followed in Group 1, 14 suffered one episode of TE. Six patients experienced major emboli; 3 of them died. Twenty of the 82 patients followed in Group 2 (no anticoagulants) suffered TE complications. There were 10 episodes of major emboli. Five of the 22 patients in Group 3 suffered an episode (all major) of TE. It is concluded from this study that anticoagulants should be given permanently to all patients with cloth-covered Starr-Edwards prostheses. Indeed, there is no period after operation when the incidence of TE is so low that anticoagulation may be safely discontinued.Keywords
This publication has 10 references indexed in Scilit:
- Late Stenosis of Starr-Edwards Cloth-Covered ProsthesesThe Annals of Thoracic Surgery, 1975
- Late Complications of Aortic Valve Replacement with Cloth-Covered, Composite-Seat Prostheses: A Six-Year AppraisalThe Annals of Thoracic Surgery, 1975
- Thrombo-embolic complications of the cloth-covered Starr-Edwards prostheses No. 2300 aortic and No. 6300 mitralThorax, 1973
- Thromboembolic complications of heart valve prosthesesAmerican Heart Journal, 1971
- Altered Platelet Function in Patients with Prosthetic Mitral Valves Effects of Sulfinpyrazone TherapyCirculation, 1970
- Cloth-covered aortic and mitral valve prosthesesThe Journal of Thoracic and Cardiovascular Surgery, 1970
- Control of Thromboembolism from Prosthetic Heart ValvesThe Annals of Thoracic Surgery, 1969
- The Development of an Autogenous Tissue Covering on Prosthetic Heart ValvesAnnals of Surgery, 1968
- Aortic Valve Replacement: A Review of Six Years' Experience with the Ball-Valve ProsthesisThe Annals of Thoracic Surgery, 1968
- Maximum utilization of the life table method in analyzing survivalJournal of Chronic Diseases, 1958