Selenium Addition to Colostrum Increases Immunoglobulin G Absorption by Newborn Calves
- 1 December 2007
- journal article
- Published by American Dairy Science Association in Journal of Dairy Science
- Vol. 90 (12), 5665-5670
- https://doi.org/10.3168/jds.2007-0348
Abstract
The objective of this study was to show a new function of Se in IgG absorption from colostrum by newborn calves. The same amount and quality of colostrum with or without Se addition was fed to paired calves (n = 60) 4 times at <2, 12, 24, and 36 h after birth, respectively. Four-time feeding of colostrum containing 1.0 ppm Se significantly increased IgG amount in the blood plasma of calves 24 h after birth; however, its effect was small (about 20% increase). Although the addition of 3.0 ppm Se once at the first colostrum feeding was more effective on IgG absorption, its significant effect was a 42% increase on average. The increased IgG concentration of blood plasma continued for about 2 wk. It is known that the absorption of colostrum IgG is mediated by intestinal pinocytosis, which continues for only 24 h after birth. The addition of Se to colostrum might directly activate this physiological pinocytosis of intestinal epithelial cells because of the rapidity of the reaction. This effect is not nutritional but rather pharmacological. Supplemented Se also resulted in its increased concentration in blood plasma. Selenium is an essential mineral for animals; however, newborn calves are always deficient in Se at birth. Application of this method in calves would also provide an immediate supply of Se and might contribute to the development of the immune system of calves. This study showed that Se supplementation to colostrum increased IgG amount and Se concentration in blood plasma in newborn calves.Keywords
This publication has 18 references indexed in Scilit:
- Selenium is inversely associated with bladder cancer risk: A report from the Belgian case–control study on bladder cancerInternational Journal of Urology, 2006
- Effect of delayed colostrum collection on colostral IgG concentration in dairy cowsJournal of the American Veterinary Medical Association, 2005
- RESPONSIVENESS OF SELENOPROTEINS TO DIETARY SELENIUM,Annual Review of Nutrition, 1999
- Effect of Dietary Selenium Supplementation on the Plasma Progesterone Concentration in Cows.The Journal of Veterinary Medical Science, 1998
- Ultrastructure of Pre‐ and Postcolostral Enterocytes of the Newborn CalfAnatomia, Histologia, Embryologia, 1996
- Incidence of production diseases and other health problems in a group of dairy herds in EnglandVeterinary Record, 1996
- Tolerance of the Preruminant Calf for Selenium in Milk ReplacerJournal of Dairy Science, 1986
- Reaction of selenium with immunoglobulin moleculesBiochimica et Biophysica Acta (BBA) - Protein Structure, 1977
- The influence of specific chemical factors in the solvent on the absorption of macromolecular substances from the small intestine of the new-born calfJournal Of Physiology-London, 1969
- Precise Fluor ometric Micro determination of Selenium in Agricultural MaterialsJournal of AOAC International, 1968