Common Virulence Factors for Bacterial Pathogenicity in Plants and Animals
- 30 June 1995
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 268 (5219), 1899-1902
- https://doi.org/10.1126/science.7604262
Abstract
A Pseudomonas aeruginosa strain (UCBPP-PA14) is infectious both in an Arabidopsis thaliana leaf infiltration model and in a mouse full-thickness skin burn model. UCBPP-PA14 exhibits ecotype specificity for Arabidopsis, causing a range of symptoms from none to severe in four different ecotypes. In the mouse model, UCBPP-PA14 is as lethal as other well-studied P. aeruginosa strains. Mutations in the UCBPP-PA14 toxA, plcS, and gacA genes resulted in a significant reduction in pathogenicity in both hosts, indicating that these genes encode virulence factors required for the full expression of pathogenicity in both plants and animals.This publication has 24 references indexed in Scilit:
- A Quantitative Model of Invasive Pseudomonas Infection in Burn InjuryJournal of Burn Care & Rehabilitation, 1994
- Global Regulation of Expression of Antifungal Factors by aPseudomonas fluorescensBiological Control StrainMolecular Plant-Microbe Interactions®, 1994
- Prokaryotic plant parasitesCell, 1993
- Characterization of thePseudomonas syringaepv.syringae61hrpJandhrpIGenes: Homology of HrpI to a Superfamily of Proteins Associated with Protein TranslocationMolecular Plant-Microbe Interactions®, 1993
- Determinants of Pathogenicity inXanthomonas campestrispv.vesicatoriaare Related to Proteins Involved in Secretion in Bacterial Pathogens of AnimalsMolecular Plant-Microbe Interactions®, 1992
- hrpGenes ofPseudomonas solanacearumare Homologous to Pathogenicity Determinants of Animal Pathogenic Bacteria and are Conserved Among Plant Pathogenic BacteriaMolecular Plant-Microbe Interactions®, 1992
- Identification and molecular mapping of a single Arabidopsis thaliana locus determining resistance to a phytopathogenic Pseudomonas syringae isolateThe Plant Journal, 1991
- Virulence of Selected Phytopathogenic Pseudomonads inArabidopsis thalianaMolecular Plant-Microbe Interactions®, 1991
- Characterization of the phospholipase C gene of Pseudomonas aeruginosa cloned in Escherichia coliGene, 1983
- Infections Caused by Pseudomonas aeruginosaClinical Infectious Diseases, 1983