Germline Inactivation of PTEN and Dysregulation of the Phosphoinositol-3-Kinase/Akt Pathway Cause Human Lhermitte-Duclos Disease in Adults
- 1 November 2003
- journal article
- Published by Elsevier BV in American Journal of Human Genetics
- Vol. 73 (5), 1191-1198
- https://doi.org/10.1086/379382
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- PTEN: One Gene, Many SyndromesHuman Mutation, 2003
- PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathwaysHuman Molecular Genetics, 2001
- Transient ectopic expression of PTEN in thyroid cancer cell lines induces cell cycle arrest and cell type-dependent cell deathHuman Molecular Genetics, 2001
- Will the real Cowden syndrome please stand up: revised diagnostic criteriaJournal of Medical Genetics, 2000
- Epigenetic PTEN Silencing in Malignant Melanomas without PTEN MutationThe American Journal of Pathology, 2000
- Mutation and Expression Analyses Reveal Differential Subcellular Compartmentalization of PTEN in Endocrine Pancreatic Tumors Compared to Normal Islet CellsThe American Journal of Pathology, 2000
- Altered PTEN Expression as a Diagnostic Marker for the Earliest Endometrial PrecancersJNCI Journal of the National Cancer Institute, 2000
- Differential Nuclear and Cytoplasmic Expression of PTEN in Normal Thyroid Tissue, and Benign and Malignant Epithelial Thyroid TumorsThe American Journal of Pathology, 2000
- Cowden Disease and Lhermitte-Duclos Disease: Characterization of a New PhakomatosisNeurosurgery, 2000
- PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death.1999