Expanding the Genetic Code of an Animal
Open Access
- 8 August 2011
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 133 (36), 14196-14199
- https://doi.org/10.1021/ja2054034
Abstract
Genetic code expansion, for the site-specific incorporation of unnatural amino acids into proteins, is currently limited to cultured cells and unicellular organisms. Here we expand the genetic code of a multicellular animal, the nematode Caenorhabditis elegans.Keywords
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