Doppler velocity detection limitations in spectrometer-based versus swept-source optical coherence tomography
Open Access
- 6 July 2011
- journal article
- Published by Optica Publishing Group in Biomedical Optics Express
- Vol. 2 (8), 2175-2188
- https://doi.org/10.1364/BOE.2.002175
Abstract
Recent advances in Doppler techniques have enabled high sensitivity imaging of biological flow to measure blood velocities and vascular perfusion. Here we compare spectrometer-based and wavelength-swept Doppler OCT implementations theoretically and experimentally, characterizing the lower and upper observable velocity limits in each configuration. We specifically characterize the washout limit for Doppler OCT, the velocity at which signal degradation results in loss of flow information, which is valid for both quantitative and qualitative flow imaging techniques. We also clearly differentiate the washout effect from the separate phenomenon of phase wrapping. We demonstrate that the maximum detectable Doppler velocity is determined by the fringe washout limit and not phase wrapping. Both theory and experimental results from phantom flow data and retinal blood flow data demonstrate the superiority of the swept-source technique for imaging vessels with high flow rates.Keywords
This publication has 49 references indexed in Scilit:
- Total retinal blood flow measurement with ultrahigh speed swept source/Fourier domain OCTBiomedical Optics Express, 2011
- Doppler variance imaging for three-dimensional retina and choroid angiographyJournal of Biomedical Optics, 2010
- Signal power decrease due to fringe washout as an extension of the limited Doppler flow measurement range in spectral domain optical coherence tomographyJournal of Biomedical Optics, 2010
- Retinal blood flow measurement by circumpapillary Fourier domain Doppler optical coherence tomographyJournal of Biomedical Optics, 2008
- Three dimensional optical angiographyOptics Express, 2007
- Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulationJournal of Biomedical Optics, 2007
- Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 13 µmOptics Express, 2005
- Frequency domain phase-resolved optical Doppler and Doppler variance tomographyOptics Communications, 2004
- Optical properties of intralipid: A phantom medium for light propagation studiesLasers in Surgery and Medicine, 1992
- The Near Infrared Absorption Spectrum of Liquid WaterJournal of the Optical Society of America, 1951