Localization of the oncogene c‐erbA1 immediately proximal to the acute promyelocytic leukaemia breakpoint on chromosome 17
- 1 July 1985
- journal article
- Published by Wiley in Annals of Human Genetics
- Vol. 49 (3), 167-171
- https://doi.org/10.1111/j.1469-1809.1985.tb01690.x
Abstract
Using in situ hybridization, c-erbA1 has been mapped immediately distal to the translocation breakpoint on chromosome 17 in fibroblasts with a karyotype 46,XX, t(15;17)(q22;q11). Previous work has shown that c-erbA1 is proximal to the translocation breakpoint on chromosome 17 in the t(15;17)(q22;q12-21) in acute promyelocytic leukaemia. The oncogene can therefore be localized to the region of chromosome 17 between the breakpoints in 17q11 and 17q12-21.Keywords
This publication has 15 references indexed in Scilit:
- A human c-erbA oncogene homologue is closely proximal to the chromosome 17 breakpoint in acute promyelocytic leukemia.Proceedings of the National Academy of Sciences, 1984
- Assignment of the haemophilia B (Factor IX) locus to the q26‐qter region of the X chromosomeAnnals of Human Genetics, 1984
- Translocated c-myc oncogene of Burkitt lymphoma is transcribed in plasma cells and repressed in lymphoblastoid cells.Proceedings of the National Academy of Sciences, 1984
- Evidence for a 15; 17 translocation in every patient with acute promyelocytic leukemiaAmerican Journal Of Medicine, 1984
- Title Page / Table of ContentsCytogenetic and Genome Research, 1983
- Genetic analysis of the 15;17 chromosome translocation associated with acute promyelocytic leukemia.Proceedings of the National Academy of Sciences of the United States of America, 1983
- t(15;17) in a promyelocytic form of chronic myeloid leukemia blastic crisisCancer Genetics and Cytogenetics, 1983
- Analysis of the breakpoints in translocation (15;17) Observed in 4 patients with acute promyelocytic leukemiaHuman Genetics, 1982
- Constitutional t(15;17)Cancer Genetics and Cytogenetics, 1981
- Proposals for the Classification of the Acute Leukaemias French‐American‐British (FAB) Co‐operative GroupBritish Journal of Haematology, 1976