Polychlorinated Biphenyls: Metabolic Behavior of Pure Isomers in Pigeons, Rats, and Brook Trout
- 20 October 1972
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 178 (4058), 312-314
- https://doi.org/10.1126/science.178.4058.312
Abstract
The metabolic behavior of pure mono-, di-, tetra-, and hexachlorobiphenyl isomers in pigeons, rats, and brook trout was investigated. Excreta from these animals were extracted and examined by chromatographic and mass spectrometric techniques. The results showed conversion of the 4-chloro-, 4,4'-dichloro-, and 2,2',5,5'-tetrachlorobiphenyl isomers into monohydroxylated derivatives by the rat and pigeon whereas no hydroxymetabolites were detected in the excreta of the brook trout. No hydroxylated products of 2,2',4,4',5,5'-hexachlorobiphenyl were detected in the excreta of pigeons, rats, or brook trout.Keywords
This publication has 8 references indexed in Scilit:
- Interpretation of Persistence and Effects of Polychlorinated Biphenyls in BirdsNature, 1972
- Beiträge zur ökologischen chemie XXXVIIIChemosphere, 1972
- Structural identification of polychlorinated biphenyls in commercial mixtures by gas-liquid chromatography, nuclear magnetic resonance and mass spectrometryJournal of Chromatography A, 1971
- Polychlorinated Biphenyls: Photolysis of 2,4,6,2′,4′,6′-HexachlorobiphenylNature, 1971
- Polychlorinated biphenyls: Synthesis of some individual chlorobiphenylsBulletin of Environmental Contamination and Toxicology, 1971
- Metabolism of a polychlorinated biphenyl (Aroclor® 1254) mixture in the ratBulletin of Environmental Contamination and Toxicology, 1971
- Studies in detoxication. 81. The metabolism of halogenobenzenes: (a) Penta- and hexa-chlorobenzenes. (b) Further observations on 1:3:5-trichlorobenzeneBiochemical Journal, 1960
- Metabolism of Biphenyl and 4-Chlorobiphenyl in the RabbitPublished by Elsevier BV ,1959