Influence of hemodynamics and intra-operative hydration on biochemical outcome of renal transplant recipients

Abstract

Background and Aims: Early graft function is crucial for successful kidney transplantation. The aim of our study was to evaluate the effect of intra-operative central venous pressure (CVP) and mean arterial pressure (MAP) on early graft function and biochemical outcome. Material and Methods: This was a retrospective study carried out on patients undergoing renal transplant only from live-related donors between March 2011 and May 2013. We mainly divided the patients into two groups based on CVP and mean MAP. One group had CVP more than 12 and other with CVP 100 mmHg and other with mean MAP of st , 2 ^nd , 3 ^rd and 4 ^th postoperative days. The mean MAP at the time of declamping was 111.22 mmHg. Mean MAP varied from a minimum of 95 mmHg to maximum of 131 mmHg. There was no significant difference in two groups on 1 ^st , 2 ^nd , 3 ^rd , 4 ^th and 5 ^th postoperative days. Conclusion: A CVP around 12 mmHg and mean MAP >95 mmHg with good perioperative fluid hydration is associated with good early graft function.