Thromboelastography Maximum Amplitude Predicts Postoperative Thrombotic Complications Including Myocardial Infarction

Abstract

The incidence of thrombotic complications with in- creased MA (8 of 95 8.4%) was significantly (P 0.0157) more frequent than that of patients with MA 68 (2 of 145 1.4%). Furthermore, the percentage suffering postoperative MI in the increased MA group (6 of 95 6.3%) was significantly larger than that in the MA 68 group (0 of 145 0%) (P 0.0035). In a multivariate analysis, increased MA (P 0.013; odds ratio, 1.16; 95% confidence interval, 1.03-1.20) and Goldman risk score (P 0.046; odds ratio, 2.39; 95% confidence interval, 1.02-5.61) both independently predicted postoperative MI. A post- operative hypercoagulable state as determined by thromboelastography is associated with postopera- tive thrombotic complications, including MI, in a diverse group of surgical patients. (Anesth Analg 2005;100:1576-83)