Ovulatory and Metabolic Effects of d-Chiro-Inositol in the Polycystic Ovary Syndrome
Open Access
- 29 April 1999
- journal article
- research article
- Published by Massachusetts Medical Society in The New England Journal of Medicine
- Vol. 340 (17), 1314-1320
- https://doi.org/10.1056/nejm199904293401703
Abstract
Women with the polycystic ovary syndrome have insulin resistance and hyperinsulinemia, possibly because of a deficiency of a d-chiro-inositol–containing phosphoglycan that mediates the action of insulin. We hypothesized that the administration of d-chiro-inositol would replenish stores of the mediator and improve insulin sensitivity.Keywords
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