Radiation-induced meningioma
- 1 May 2008
- journal article
- portrait
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Neurosurgical Focus
- Vol. 24 (5), E7
- https://doi.org/10.3171/foc/2008/24/5/e7
Abstract
The long-term or delayed side effects of irradiation on neural tissue are now known to include the induction of new central nervous system neoplasms. However, during the first half of the 20th century, human neural tissue was generally considered relatively resistant to the carcinogenic and other ill effects of ionizing radiation. As a result, exposure to relatively high doses of x-rays from diagnostic examinations and therapeutic treatment was common. In the present article the authors review the literature relating to radiation-induced meningiomas (RIMs). Emphasis is placed on meningiomas resulting from childhood treatment for primary brain tumor or tinea capitis, exposure to dental x-rays, and exposure to atomic explosions in Hiroshima and Nagasaki. The incidence and natural history of RIMs following exposure to high- and low-dose radiation is presented, including latency, multiplicity, histopathological features, and recurrence rates. The authors review the typical presentation of patients with RIMs and discuss unique aspects of the surgical management of these tumors compared with sporadic meningioma, based on their clinical experience in treating these lesions.Keywords
This publication has 69 references indexed in Scilit:
- Malignant progression in meningioma: documentation of a series and analysis of cytogenetic findingsJournal of Neurosurgery, 2004
- Intracranial meningiomas following irradiation-a growing problem?British Journal of Neurosurgery, 1995
- Intracranial meningiomas among Nagasaki atomic bomb survivorsThe Lancet, 1994
- A phase II evaluation of tamoxifen in unresectable or refractory meningiomas: a southwest oncology group studyJournal of Neuro-Oncology, 1993
- Tumors of the Brain and Nervous System after Radiotherapy in ChildhoodThe New England Journal of Medicine, 1988
- Seemingly complete removal of histologically benign intracranial meningioma: Late recurrence rate and factors predicting recurrence in 657 patients. A multivariate analysisSurgical Neurology, 1986
- Recurrence of intracranial meningiomas: the role played by regional multicentricityJournal of Neurosurgery, 1986
- Radiation-induced cerebral meningioma: a recognizable entityJournal of Neurosurgery, 1984
- THE LESSONS OF RADIOBIOLOGY FOR DIAGNOSTIC RADIOLOGYAmerican Journal of Roentgenology, 1973
- CHRONIC RINGWORM INFECTION OF THE SKIN AND NAILS TREATED WITH GRISEOFULVIN REPORT OF A THERAPEUTIC TRIALThe Lancet, 1960