Breastfeeding Prevents Severe Disease in Full Term Female Infants With Acute Respiratory Infection
- 1 February 2009
- journal article
- Published by Ovid Technologies (Wolters Kluwer Health) in The Pediatric Infectious Disease Journal
- Vol. 28 (2), 131-134
- https://doi.org/10.1097/inf.0b013e31818a8a82
Abstract
Breastfeeding is a well-known protective factor against severe respiratory tract infections. Recently, a gender specific role for human milk has been described in very low birth weight infants and neonates: breast milk protected girls but not boys. To determine whether the protective effect of breastfeeding on the severity of acute respiratory infections in full term infants is different for girls and boys. A prospective cross-sectional study of infants seeking medical care for acute respiratory infection. The protective role of breastfeeding against viral pneumonia and hospitalization were assessed by univariate and multivariate analyses. Analyses were adjusted for important confounders. A total of 323 patients were enrolled in this study. Breastfeeding protected girls against pneumonia and hospitalization, but did not protect boys. Nonbreastfeeding females were particularly susceptible to severe acute respiratory infections. Breastfeeding had a protective effect against severe disease in infant girls experiencing their first symptomatic respiratory infection. Nonbreastfeeding females are at significant risk for severe acute lung disease and should be targeted intensively by breastfeeding campaigns.Keywords
This publication has 16 references indexed in Scilit:
- Differential Gender Response to Respiratory Infections and to the Protective Effect of Breast Milk in Preterm InfantsPEDIATRICS, 2008
- Role of Respiratory Viruses in Acute Upper and Lower Respiratory Tract Illness in the First Year of LifeThe Pediatric Infectious Disease Journal, 2006
- Full Breastfeeding and Hospitalization as a Result of Infections in the First Year of LifePEDIATRICS, 2006
- Severity of Respiratory Syncytial Virus Bronchiolitis Is Affected by Cigarette Smoke Exposure and AtopyPEDIATRICS, 2005
- Crowding: risk factor or protective factor for lower respiratory disease in young children?BMC Public Health, 2004
- Environmental and demographic risk factors for respiratory syncytial virus lower respiratory tract diseaseThe Journal of Pediatrics, 2003
- Reduced Risk of Neonatal Respiratory Infections Among Breastfed Girls but Not BoysPEDIATRICS, 2003
- Breastfeeding and the Risk of Hospitalization for Respiratory Disease in InfancyArchives of Pediatrics & Adolescent Medicine, 2003
- Socioeconomic environmental factors and hospitalization for acute bronchiolitis during infancyActa Paediatrica, 2002
- Respiratory Syncytial Virus and Parainfluenza VirusThe New England Journal of Medicine, 2001