Undifferentiated Sinonasal Carcinoma in a Patient With Nevoid Basal Cell Carcinoma Syndrome
- 26 July 2007
- journal article
- case report
- Published by SAGE Publications in International Journal of Surgical Pathology
- Vol. 15 (3), 303-306
- https://doi.org/10.1177/1066896907302362
Abstract
Nevoid basal cell carcinoma syndrome is an autosomal dominant multisystem disorder characterized by developmental anomalies and occurrence of multiple basal cell carcinomas and other tumors in early childhood. In this article, the authors report a case of a 19-year-old African American male with nevoid basal cell carcinoma syndrome and a history of medulloblastoma at age 2, meningioma at age 14, thyroid follicular adenomas with papillary carcinoma at age 15, and 2 basal cell carcinomas at ages 16 and 18. Recently, he developed sinonasal undifferentiated carcinoma (SNUC). The radiology and pathology of the sinonasal carcinoma are presented in this report. Review of the literature reveals that this is the first case of SNUC occurring in a patient with nevoid basal cell carcinoma syndrome.Keywords
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