Measuring Response with FDG-PET: Methodological Aspects
- 1 April 2009
- journal article
- review article
- Published by Oxford University Press (OUP) in The Oncologist
- Vol. 14 (4), 369-377
- https://doi.org/10.1634/theoncologist.2008-0119
Abstract
The use of fluorodeoxyglucose positron emission tomography (FDG-PET) for the evaluation of tumor response to chemotherapy and radiation therapy has been studied in a number of malignancies. By imaging tumor metabolism and therapy-related changes, FDG-PET has demonstrated advantages over anatomical imaging in the assessment of treatment response. More recent investigations have indicated that FDG-PET can predict tumor response early during the course of therapy, potentially allowing for early treatment adjustments. The aim of this review is to provide oncologists with a basic knowledge of the practical aspects of PET quantification for treatment.Keywords
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