Assessment of Human Health Risks of Consumption of Cadmium Contaminated Cultured Oysters
- 19 March 2007
- journal article
- research article
- Published by Taylor & Francis Ltd in Human and Ecological Risk Assessment: An International Journal
- Vol. 13 (2), 370-382
- https://doi.org/10.1080/10807030701226301
Abstract
With farmed British Columbia (BC) oysters containing higher cadmium concentrations than wild oysters, long-term exposure to cadmium through consumption of oysters has the potential to cause health risks. This study reports on a risk assessment for cadmium intake resulting from the consumption of BC-cultured oyster. The study concludes that Health Canada's current recommended BC-cultured oyster consumption rate for Canadians of 12 oysters per month exceeds the Agency for Toxic Substances and Disease Registry chronic oral minimal risk levels (MRL) of 0.2 μ g·kg− 1·day− 1 by approximately 4-to 5-fold and reaches the Food and Agriculture Organization/World Health Organization (FAP/WHO) reference dose of 1 μg·kg−1·day−1 for cadmium consumption for Canadians. This suggests that although the current recommended maximum oyster consumption rates is consistent with the FAO/WHO and U.S. Environmental Protection Agency limits for acceptable risk, it leaves little or no room for error or uncertainty. This is noteworthy as recent studies demonstrate toxicological effects at cadmium intakes of 0.43 to 0.71 μ gCd·kg−1·day−1. This study indicates that a lower maximum BC-cultured oyster rate should be considered, particularly for high risk groups, including women with low iron stores, people with renal impairment, smokers, children, and indigenous people who consume organ meats of games and wildlife other than shellfish.Keywords
This publication has 22 references indexed in Scilit:
- Adverse Health Effects of Chronic Exposure to Low-Level Cadmium in Foodstuffs and Cigarette SmokeEnvironmental Health Perspectives, 2004
- Cadmium and Its Health Effects. Low Dose Exposure to Cadmium and Its Health Effects. (2). Life-cycle Related Diseases and Reproductive Toxicity.Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene), 2002
- Risk assessment of cadmium exposure in Fort Resolution, Northwest Territories, CanadaFood Additives & Contaminants, 1998
- The influence of nutritional deficiencies on gastrointestinal uptake of cadmium and cadmium-metallothionein in ratsToxicology, 1995
- Determination of cadmium and lead in foods by graphite furnace atomic absorption spectrometry with Zeeman background correction: Test with certified reference materialsFood Additives & Contaminants, 1990
- Dietary intakes of lead, cadmium, arsenic and fluoride by Canadian adults: A 24‐hour duplicate diet studyFood Additives & Contaminants, 1987
- Dietary Exposure to Cadmium and Health Effects: Impact of Environmental ChangesEnvironmental Health Perspectives, 1985
- Conceptual problems in establishing the critical concentration of cadmium in human kidney cortexEnvironmental Research, 1984
- Metabolic Model for Cadmium in ManEnvironmental Health Perspectives, 1979
- A kinetic model of cadmium metabolism in the human beingEnvironmental Research, 1978