Latino populations: a unique opportunity for epidemiological research of asthma
Open Access
- 11 October 2007
- journal article
- review article
- Published by Wiley in Paediatric and Perinatal Epidemiology
- Vol. 21 (s3), 15-22
- https://doi.org/10.1111/j.1365-3016.2007.00880.x
Abstract
Asthma is a significant health problem among Latinos, the largest minority population in the US. Asthma prevalence, morbidity and mortality are highest in Puerto Ricans, intermediate in Dominicans and Cubans, and lowest in Mexicans and Central Americans. From a cultural and social perspective, Latinos represent a wide variety of national origins and ethnic and cultural groups, with a full spectrum of social class. From a genetic perspective, Latinos have descended from Native American, European and African populations. Here, we review results from recent genetic and clinical studies to illustrate the unique opportunity Latino groups offer for studying the interaction between racial, genetic and environmental contributions to asthma and drug responsiveness.Keywords
This publication has 36 references indexed in Scilit:
- Ancestry–Environment Interactions and Asthma Risk among Puerto RicansAmerican Journal of Respiratory and Critical Care Medicine, 2006
- Prevalence of Childhood Asthma in Urban Communities: The Impact of Ethnicity and IncomeAnnals of Epidemiology, 2006
- Population stratification confounds genetic association studies among LatinosHuman Genetics, 2005
- Demonstrating stratification in a European American populationNature Genetics, 2005
- Estimation of individual admixture: Analytical and study design considerationsGenetic Epidemiology, 2005
- Admixture mapping for hypertension loci with genome-scan markersNature Genetics, 2005
- Tobacco smoking increases dramatically air concentrations of endotoxinIndoor Air, 2004
- Parent-reported asthma in Puerto Rican childrenPediatric Pulmonology, 2004
- Census, race and scienceNature Genetics, 2000
- Use of Unlinked Genetic Markers to Detect Population Stratification in Association StudiesAmerican Journal of Human Genetics, 1999