LONG‐TERM SUPPRESSION OF A TESTOSTERONE‐PRODUCING OVARIAN TUMOUR BY OESTROGEN/PROGESTOGEN THERAPY

Abstract
A 44-year-old lady presenting with hirsuitism was found to have a testosterone-secreting Leydig cell tumour of the right ovary. Serum testoterone levels were adequately suppressed for 8 years by combined oestrogen/progestogen preparation (Microgynon 30, Schering, West Sussex). The fall in gonadotrophin and tesosterone levels during therapy and their rise after stopping therapy suggests that the tumour was gonadotrophin dependent.