Clinical Features of Narcolepsy: Japanese Experiences

Abstract

In this chapter, narcolepsy is discussed from the clinical point of view. Several areas of recent concern in research are described based on my personal experiences with Japanese narcoleptic patients. There is a large Japanese literature on narcolepsy which has not been known to the researchers of other countries because of the language barrier. Some of these studies are cited and explained briefly. First, the symptomatology associated with narcolepsy is discussed. This leads to the definition of the term “narcolepsy” and issues in the diagnostic criteria for narcolepsy and in differential diagnosis. Next, the pathophysiology of narcolepsy, neuroendocrine, neuropharmacological, and epidemiological findings are described, followed by recommendations of practical treatment plans and an introduction of the activities of the Japan Narcolepsy Association.