The relevance of cardio-pulmonary-vascular reflex to regulation of the brain vessels.

Abstract

In 11 cordotomized (C2) rats with the vagi cut, monopolar electrical stimulation at a current intensity of 73 +/- 21 (S.E.) microA (n = 6) to the intermediate region of the solitary nucleus elicited an increase (p less than 0.05) in regional blood flow (iodoantipyrine technique) of 71% and 43% in the frontal cortex and caudate nucleus, respectively. The findings suggest that some of the cardio-pulmonary and cardio-vascular reflex mechanisms are involved in the regulation of the blood vessels of the brain.