Challenge of conducting a placebo-controlled randomized efficacy study for influenza vaccine in a season with low attack rate and a mismatched vaccine B strain: a concrete example
Open Access
- 17 January 2009
- journal article
- research article
- Published by Springer Science and Business Media LLC in BMC Infectious Diseases
- Vol. 9 (1), 2
- https://doi.org/10.1186/1471-2334-9-2
Abstract
Our aim was to determine the efficacy of a trivalent inactivated split virus influenza vaccine (TIV) against culture-confirmed influenza A and/or B in adults 18 to 64 years of age during the 2005/2006 season in the Czech Republic.Keywords
This publication has 30 references indexed in Scilit:
- Prevention of Symptomatic Seasonal Influenza in 2005–2006 by Inactivated and Live Attenuated VaccinesThe Journal of Infectious Diseases, 2008
- Vaccines for preventing influenza in healthy childrenPublished by Wiley ,2008
- Prevention of Antigenically Drifted Influenza by Inactivated and Live Attenuated VaccinesNew England Journal of Medicine, 2006
- Influenza vaccination: policy versus evidenceBMJ, 2006
- Prevention of influenza in the general populationCMAJ : Canadian Medical Association Journal, 2004
- Vaccines for preventing influenza in healthy adultsPublished by Wiley ,2004
- Recent changes among human influenza virusesVirus Research, 2004
- Ten Years of Experience with the Trivalent Split-Influenza Vaccine, Fluarix???Clinical Drug Investigation, 2002
- Antigenic and Genetic Characterization of the Haemagglutinins of Recent Cocirculating Strains of Influenza B VirusJournal of General Virology, 1992
- Cocirculation of two distinct evolutionary lineages of influenza type B virus since 1983Virology, 1990