Repellency of deet and SS220 applied to skin involves olfactory sensing by two species of ticks
- 4 March 2005
- journal article
- research article
- Published by Wiley in Medical and Veterinary Entomology
- Vol. 19 (1), 101-106
- https://doi.org/10.1111/j.0269-283x.2005.00559.x
Abstract
Responses of host-seeking nymphs of the blacklegged tick, Ixodes scapularis Say and lone star tick, Amblyomma americanum (Linnaeus) (Acari: Ixodidae) to the repellents N,N-diethyl-3-methylbenzamide (deet) and (1S, 2'S)-2-methylpiperidinyl-3-cyclohexene-1-carboxamide (SS220) were studied using fingertip laboratory bioassays. Ethanol solutions of both compounds applied to the skin strongly repelled both species of ticks at 0.8 and 1.6 micromole of compound/cm2 skin. The ticks were also repelled when two layers of organdie cloth covered the portion of a finger treated with either deet or SS220. Gas chromatographic analyses of the outer layer of cloth that had covered skin treated with 1.6 micromole compound/cm2 skin revealed only 0.1 nmole SS220/cm2 cloth and 2.8 nmole deet/cm2 cloth. However, in bioassays in which a single layer of cloth was treated with a dose of deet or SS220 equivalent to the amount found in the outer layer of cloth, ticks were not repelled. Results unequivocally demonstrated that these ticks responded to the repellents in the vapour phase when repellent treated skin was covered with cloth to obviate tactile contact with them, and made it clear that the ticks detect the repellents by olfactory sensing. Heretofore, the mode of action of deet and SS220 was unclear.Keywords
This publication has 19 references indexed in Scilit:
- The ‘4-Poster’ Passive Topical Treatment Device to Apply Acaricide for Controlling Ticks (Acari: Ixodidae) Feeding on White-Tailed DeerJournal of Medical Entomology, 2000
- A novel test system for detection of tick repellentsEntomologia Experimentalis et Applicata, 1999
- Emergence of the Ehrlichioses as Human Health ProblemsEmerging Infectious Diseases, 1996
- Ehrlichial Diseases of Humans: Emerging Tick-Borne InfectionsClinical Infectious Diseases, 1995
- Ecology of Ixodes Dammini-Borne Human Babesiosis and Lyme DiseaseAnnual Review of Entomology, 1985
- Ecology of Ixodes Dammini-Borne Human Basesiosis and Lyme DiseaseAnnual Review of Entomology, 1985
- Efficacy of Permethrin as a Repellent and Toxicant for Personal Protection Against the Pacific Coast Tick and the Pajaroello Tick (Acari: Ixodidae and Argasidae)Journal of Medical Entomology, 1984
- Pressurized Sprays of Permethrin and deet on Clothing for Personal Protection Against the Lone Star Tick and the American Dog Tick (Acari: Ixodidae)1Journal of Economic Entomology, 1983
- The Sensory Basis of Tick Feeding BehaviourPublished by Elsevier BV ,1982