Mixed Lineage Kinase 3 deficiency delays viral clearance in the lung and is associated with diminished influenza-induced cytopathic effect in infected cells
- 10 May 2010
- journal article
- Published by Elsevier BV in Virology
- Vol. 400 (2), 224-232
- https://doi.org/10.1016/j.virol.2010.02.001
Abstract
No abstract availableKeywords
Funding Information
- RO1 HL75432
- HL088325
- RO1 HL083761
- NS054578
- MH64570
- HHSN266200700008C
- NIH (T32 AI007362)
This publication has 44 references indexed in Scilit:
- Lethal Influenza Virus Infection in Macaques Is Associated with Early Dysregulation of Inflammatory Related GenesPLoS Pathogens, 2009
- Infection of HLA-DR1 Transgenic Mice with a Human Isolate of Influenza A Virus (H1N1) Primes a Diverse CD4 T-Cell Repertoire That Includes CD4 T Cells with Heterosubtypic Cross-Reactivity to Avian (H5N1) Influenza VirusJournal of Virology, 2009
- Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virusProceedings of the National Academy of Sciences, 2009
- H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of MicePLoS Pathogens, 2008
- Pathology, Molecular Biology, and Pathogenesis of Avian Influenza A (H5N1) Infection in HumansThe American Journal of Pathology, 2008
- Direct Ex Vivo Analyses of HLA-DR1 Transgenic Mice Reveal an Exceptionally Broad Pattern of Immunodominance in the Primary HLA-DR1-Restricted CD4 T-Cell Response to Influenza Virus HemagglutininJournal of Virology, 2007
- Mixed lineage kinases (MLKs): a role in dendritic cells, inflammation and immunity?International Journal of Experimental Pathology, 2007
- Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virusNature, 2006
- Inhibition of Transforming Growth Factor-β1–induced Signaling and Epithelial-to-Mesenchymal Transition by the Smad-binding Peptide Aptamer Trx-SARAMolecular Biology of the Cell, 2006
- Mixed Lineage Kinase 3 (MLK3)-activated p38 MAP Kinase Mediates Transforming Growth Factor-β-induced Apoptosis in Hepatoma CellsJournal of Biological Chemistry, 2004