Early and Presenting Symptoms of Dementia with Lewy Bodies
- 16 November 2011
- journal article
- Published by S. Karger AG in Dementia and Geriatric Cognitive Disorders
- Vol. 32 (3), 202-208
- https://doi.org/10.1159/000333072
Abstract
To explore the presenting and early symptoms of dementia with Lewy bodies (DLB). Patients with mild dementia fulfilling diagnostic criteria for DLB (n = 61) and Alzheimer's disease (AD) (n = 109) were recruited from outpatient dementia clinics in western Norway. At diagnosis, caregivers were asked which symptom had been the presenting symptom of dementia. Caregivers reported that memory impairment was the most common presenting symptom in DLB (57%), followed by visual hallucinations (44%), depression (34%), problem solving difficulties (33%), gait problems (28%), and tremor/stiffness (25%). In contrast, 99% of AD carers reported impaired memory as a presenting symptom, whereas visual hallucinations were a presenting symptom in 3% of the AD cases. DLB should be suspected in predementia cases with visual hallucinations.Keywords
This publication has 34 references indexed in Scilit:
- Decreased striatal dopamine transporter uptake and substantia nigra hyperechogenicity as risk markers of synucleinopathy in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective studyThe Lancet Neurology, 2010
- Prodromal clinical manifestations of neuropathologically confirmed Lewy body diseaseNeurobiology of Aging, 2010
- REM sleep behavior disorder preceding other aspects of synucleinopathies by up to half a centuryNeurology, 2010
- Mild cognitive impairment associated with limbic and neocortical lewy body disease: a clinicopathological studyBrain, 2009
- High Prevalence of Orthostatic Hypotension in Mild DementiaDementia and Geriatric Cognitive Disorders, 2009
- Frequency and Case Identification of Dementia with Lewy Bodies Using the Revised Consensus CriteriaDementia and Geriatric Cognitive Disorders, 2008
- Patients With Dementia With Lewy Bodies Have More Impaired Quality of Life Than Patients With Alzheimer DiseaseAlzheimer Disease & Associated Disorders, 2007
- Patients with Lewy body dementia use more resources than those with Alzheimer's diseaseInternational Journal of Geriatric Psychiatry, 2006
- Survival and mortality differences between dementia with Lewy bodies vs Alzheimer diseaseNeurology, 2006
- Diagnosis and management of dementia with Lewy bodiesNeurology, 2005