Body mass and probability of pregnancy during assisted reproduction treatment: retrospective study

Abstract

The participants were 3586 women who received assisted reproduction treatment between 1987 and 1998 in a tertiary medical unit in Adelaide, South Australia. Treatments included in vitro fertilisation (n=1972), intracytoplasmic sperm injection (n=1040), and gamete intrafallopian transfer (n=574). Patients underwent 8822 embryo transfer cycles. The overall implantation rate was 12.0%, and the clinical pregnancy rate was 24.1% in the study population. Causes of infertility included tubal blockage (34%), semen defects (35%), unexplained infertility (16%), and endometriosis (9%). Age of participants, treatment modalities, location of the treatment, number of embryos transferred, number of cycles of embryo transfer, and number of oocytes recovered were analysed to eliminate possible confounding effects. Polycystic ovarian syndrome was diagnosed, using normal criteria, in 25% (881/3586) of the women.3