Pneumonitis and pulmonary haemorrhage after acute myocardial infarction
- 1 December 2015
- journal article
- case report
- Published by Elsevier BV in Clinical Medicine
- Vol. 15 (6), 591-593
- https://doi.org/10.7861/clinmedicine.15-6-591
Abstract
A 55-year-old man presented with acute ST-elevation myocardial infarction. He received rescue angioplasty with one drug eluting stent. He developed marked breathlessness and haemoptysis two days later. Investigations led to the diagnosis of pulmonary haemorrhage, possibly from pneumonitis caused by ticagrelor. He was successfully managed with high-dose steroids and ticagrelor was replaced with clopidogrel. On stopping the steroids a month later, mild haemoptysis recurred and this was managed conservatively. Pneumonitis and pulmonary haemorrhage is rarely reported with acute myocardial infarction, but poses serious challenge to the patient and the clinician. Diagnosis may be delayed as breathlessness can occur due to myriad causes after myocardial infarction. Interrupting dual anti-platelet therapy after angioplasty could lead to devastating stent thrombosis.Keywords
This publication has 8 references indexed in Scilit:
- A Case of Pulmonary Hemorrhage Due to Drug-Induced Pneumonitis Secondary to Ticagrelor TherapySocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 2014
- 2012 ACCF/AHA Focused Update of the Guideline for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction (Updating the 2007 Guideline and Replacing the 2011 Focused Update)Journal of the American College of Cardiology, 2012
- Ticagrelor versus Clopidogrel in Patients with Acute Coronary SyndromesThe New England Journal of Medicine, 2009
- Diffuse alveolar hemorrhage: diagnosing it and finding the cause.Cleveland Clinic Journal of Medicine, 2008
- Heparin and Low-Molecular-Weight HeparinSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 2004
- Pharmacokinetics and Pharmacodynamics of Tenecteplase in Fibrinolytic Therapy of Acute Myocardial InfarctionClinical Pharmacokinetics, 2002
- Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE studyThe Lancet, 2001
- Coronary artery stent placement with postprocedural antiplatelet therapy in acute myocardial infarctionCoronary Artery Disease, 1998