A Novel Device for the Evaluation of Hemostatic Function in Critical Care Settings
- 1 December 2016
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Anesthesia & Analgesia
- Vol. 123 (6), 1372-1379
- https://doi.org/10.1213/ane.0000000000001413
Abstract
Major surgical procedures often result in significant intra- and postoperative bleeding. The ability to identify the cause of the bleeding has the potential to reduce the transfusion of blood products and improve patient care. We present a novel device, the Quantra Hemostasis Analyzer, which has been designed for automated, rapid, near-patient monitoring of hemostasis. The Quantra is based on Sonic Estimation of Elasticity via Resonance Sonorheometry, a proprietary technology that uses ultrasound to measure clot time and clot stiffness from changes in viscoelastic properties of whole blood during coagulation. We present results of internal validation and analytical performance testing of the technology and demonstrate the ability to characterize the key functional components of hemostasis.This publication has 26 references indexed in Scilit:
- Principles and Practice of Thromboelastography in Clinical Coagulation Management and Transfusion PracticeTransfusion Medicine Reviews, 2012
- Adaptive force sonorheometry for assessment of whole blood coagulationClinica Chimica Acta; International Journal of Clinical Chemistry, 2010
- Multidisciplinary Approach to the Challenge of HemostasisAnesthesia & Analgesia, 2010
- A novel ultrasound-based method to evaluate hemostatic function of whole bloodClinica Chimica Acta; International Journal of Clinical Chemistry, 2010
- Cost reduction of perioperative coagulation management in cardiac surgery: value of ‘bedside’ thrombelastography (ROTEM)☆European Journal of Cardio-Thoracic Surgery, 2007
- The Predictive Value of Modified Computerized Thromboelastography and Platelet Function Analysis for Postoperative Blood Loss in Routine Cardiac SurgeryAnesthesia & Analgesia, 2003
- The Predictive Value of Modified Computerized Thromboelastography and Platelet Function Analysis for Postoperative Blood Loss in Routine Cardiac SurgeryAnesthesia & Analgesia, 2003
- Effects of Unfractionated Heparin, Low-Molecular-Weight Heparin, and Heparinoid on Thromboelastographic Assay of Blood CoagulationAmerican Journal of Clinical Pathology, 2000
- Thromboelastography-Guided Transfusion Algorithm Reduces Transfusions in Complex Cardiac SurgeryAnesthesia & Analgesia, 1999
- Thromboelastography-Guided Transfusion Algorithm Reduces Transfusions in Complex Cardiac SurgeryAnesthesia & Analgesia, 1999