A Facile Electrochemical Method for Synthesis of New Benzofuran Derivatives
- 12 March 2004
- journal article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 69 (7), 2637-2640
- https://doi.org/10.1021/jo035304t
Abstract
Electrooxidation of 3-substituted catechols has been studied in the presence of dimedone in aqueous solution, using cyclic voltammetry and controlled-potential coulometry. The results indicate that the quinones derived from catechols participate in Michael addition reactions with dimedone to form the corresponding benzofuran derivatives (6a-c). We propose a mechanism for the electrode process. The efficient electrochemical synthesis of 6a-c has been performed at carbon rod electrodes in an undivided cell using a constant current.This publication has 16 references indexed in Scilit:
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