Novel 8,9-dihydroxy-7-methyl-12H-benzothiazolo[2,3-b]quinazolin-12-one multiwalled carbon nanotubes paste electrode for simultaneous determination of ascorbic acid, acetaminophen and tryptophan
- 16 July 2012
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Analytical Methods
- Vol. 4 (10), 3275-3282
- https://doi.org/10.1039/c2ay25418b
Abstract
The electrooxidation of ascorbic acid (AA), acetaminophen (AC), tryptophan (Trp), and their mixture has been studied using an 8,9-dihydroxy-7-methyl-12H-benzothiazolo[2,3-b]quinazolin-12-one modified carbon nanotubes paste electrode and cyclic voltammetry, chronoamperometry, electrochemical impedance spectroscopy and square wave voltammetry methods. The sensor exhibited potent and persistent electron mediating behavior followed by well separated oxidation peaks towards AA, AC and Trp with activation overpotential. The linear response range for AA, AC and Trp were 0.07–350, 3.0–600, and 10.0–700 μM, respectively. The modified electrode was used for the determination of these compounds in biological and pharmaceutical samples.Keywords
This publication has 70 references indexed in Scilit:
- Simultaneous Determination of Ascorbic Acid, Acetaminophen, and Tryptophan by Square Wave Voltammetry Using N‐(3,4‐Dihydroxyphenethyl)‐3,5‐Dinitrobenzamide‐Modified Carbon Nanotubes Paste ElectrodeElectroanalysis, 2012
- A Voltammetric Sensor Based on Modified Multiwall Carbon Nanotubes for Cysteamine Determination in the Presence of Tryptophan Using p‐Aminophenol as a MediatorElectroanalysis, 2010
- Simultaneous Determination of Paracetamol, Ascorbic Acid and Codeine by Differential Pulse Voltammetry on the Aluminum Electrode Modified by Thin Layer of PalladiumElectroanalysis, 2010
- Electrochemical Oxidation and Sensitive Determination of Acetaminophen in Pharmaceuticals at Poly(3,4‐ethylenedioxythiophene)‐Modified Screen‐Printed ElectrodesElectroanalysis, 2010
- Carbon Paste Electrode Incorporating 1‐[4‐(Ferrocenyl Ethynyl) Phenyl]‐1‐Ethanone for Electrocatalytic and Voltammetric Determination of TryptophanElectroanalysis, 2008
- Electrocatalytic Determination of Ascorbic Acid at the Surface of 2,7‐Bis(ferrocenyl ethyl)fluoren‐9‐one Modified Carbon Paste ElectrodeElectroanalysis, 2006
- Determination of Ascorbic Acid and Dehydroascorbic Acid in Biological Samples by High-Performance Liquid Chromatography Using Subtraction Methods: Reliable Reduction with Tris[2-carboxyethyl]phosphine HydrochlorideAnalytical Biochemistry, 2000
- Pharmacokinetic Investigations with Direct Injection of Plasma Samples: Possible Savings Using Capillary Electrophoresis (CE)Archiv der Pharmazie, 1999
- Determination of pharmaceuticals in plasma by capillary electrophoresis without sample pretreatment reproducibility, limit of quantitation and limit of detectionElectrophoresis, 1997
- Drug Biotransformation Interactions in Man VI: Acetaminophen and Ascorbic AcidJournal of Pharmaceutical Sciences, 1976