Self‐Ratings of Olfactory Function Reflect Odor Annoyance Rather than Olfactory Acuity
- 1 December 2008
- journal article
- research article
- Published by Wiley in The Laryngoscope
- Vol. 118 (12), 2212-2217
- https://doi.org/10.1097/mlg.0b013e3181826e43
Abstract
Objective/Hypothesis: Self-ratings of olfactory function often correlates poorly with results of objective smell tests. We explored these ratings relative to self-rating of odor annoyance, to odor identification ability, and to mean perceived intensity of odors, and estimated relative genetic and environmental contributions to these traits. Participants and Methods: A total of 1,311 individual twins from the general population (62% females and 38% males, aged 10-83 years, mean age 29 years) including 191 monozygous and 343 dizygous complete twin pairs from Australia, Denmark, Finland, and the United Kingdom rated their sense of smell and annoyance caused by ambient smells (e.g., smells of foods) using seven categories, and performed odor identification and evaluation task for six scratch-and-sniff odor stimuli. Results: The self-rating of olfactory function correlated with the self-rating of odor annoyance (r = 0.30) but neither correlated with the odor identification score. Quantitative genetic modeling revealed no unambiguously significant genetic contribution to variation in any of the studied traits. Conclusion: The results suggest that environmental rather than genetic factors modify the self-rating of olfactory function and support earlier findings of discrepancy between subjective and objective measures of olfactory function. In addition, the results imply that the self-rating of olfactory function arises from experienced odor annoyance rather than from actual olfactory acuity.Keywords
This publication has 34 references indexed in Scilit:
- Genetic Elucidation of Human Hyperosmia to Isovaleric AcidPLoS Biology, 2007
- Lateralized Differences in Olfactory FunctionThe Laryngoscope, 2007
- Olfactory loss may be a first sign of idiopathic Parkinson's diseaseMovement Disorders, 2007
- Genetic component of identification, intensity and pleasantness of odours: a Finnish family studyEuropean Journal of Human Genetics, 2007
- The UK Adult Twin Registry (TwinsUK)Twin Research and Human Genetics, 2006
- Twin Studies in Finland 2006Twin Research and Human Genetics, 2006
- The Danish Twin Registry in the New MillenniumTwin Research and Human Genetics, 2006
- Clinical Significance of Results from Olfactory TestingThe Laryngoscope, 2006
- Unawareness of Smell Loss in Normal Aging and Alzheimer's Disease: Discrepancy between Self-Reported and Diagnosed Smell SensitivityThe Journals of Gerontology, Series B: Psychological Sciences and Social Sciences, 1995
- Olfactory Sensitivity in Humans: Genetic Versus Environmental ControlScience, 1980