Bone Texture Analysis on Direct Digital Radiographic Images: Precision Study and Relationship with Bone Mineral Density at the Os Calcis
- 2 February 2007
- journal article
- research article
- Published by Springer Science and Business Media LLC in Calcified Tissue International
- Vol. 80 (2), 97-102
- https://doi.org/10.1007/s00223-006-0216-y
Abstract
Assessment of bone microarchitecture in complement to bone mineral density (BMD) exam could improve prediction of osteoporotic fractures. A high-resolution X-ray prototype was developed to assess microarchitecture quality. Images were obtained on os calcis; then, three texture parameters were calculated on the same region of interest (ROI): a fractal parameter, a run-length parameter, and a co-occurrence parameter. This work describes the reproducibility of this method. We also examine the relationship between texture parameters and BMD at a site-matched ROI. Measurements on the left heel were performed on 30 healthy women, on the same day, with repositioning for short-term precision error. An additional measurement was done at 1 week to evaluate mid-term precision error on 14 subjects. Os calcis images from 10 healthy women were used to evaluate both intra- and interobserver reproducibility. Thirty other healthy patients were measured successively on two similar devices for interprototype comparison. BMD and texture analyses of the left heel were obtained from 57 women. Short-term precision errors ranged 1.16–1.24% according to the texture parameter. Mid-term precision error was slightly higher than short-term precision for the mean Hurst exponent parameter. Comparisons of texture parameters and BMD at a site-matched ROI on the os calcis showed no significant relationships. The results also show that the use of this high-resolution digital X-ray device improves the reproducibility of parameter measurement compared to the indirect digitization of radiologic films previously used.Keywords
This publication has 36 references indexed in Scilit:
- Imaging techniques for evaluating bone microarchitectureJoint Bone Spine, 2006
- Bone Quality — The Material and Structural Basis of Bone Strength and FragilityNew England Journal of Medicine, 2006
- BMD at Multiple Sites and Risk of Fracture of Multiple Types: Long-Term Results From the Study of Osteoporotic FracturesJournal of Bone and Mineral Research, 2003
- Bone strength and its determinantsOsteoporosis International, 2003
- Suitability of texture features to assess changes in trabecular bone architecturePattern Recognition Letters, 2002
- Mechanical Consequences of Bone Loss in Cancellous BoneJournal of Bone and Mineral Research, 2001
- Fractal analysis of radiographs: Assessment of trabecular bone structure and prediction of elastic modulus and strengthMedical Physics, 1999
- Fractal Analysis of Proximal Femur Radiographs: Correlation with Biomechanical Properties and Bone Mineral DensityOsteoporosis International, 1999
- Consensus development conference: Diagnosis, prophylaxis, and treatment of osteoporosisAmerican Journal Of Medicine, 1993
- Ability of four different techniques of measuring bone mass to diagnose vertebral fractures in postmenopausal womenJournal of Bone and Mineral Research, 1987