TBHP-Mediated Oxidative Cross-Coupling of Disulfides with Ethers through a C(sp3)-H Thiolation Process
- 9 June 2014
- journal article
- research article
- Published by Taylor & Francis Ltd in Synthetic Communications
- Vol. 44 (14), 2045-2050
- https://doi.org/10.1080/00397911.2014.888081
Abstract
A new tert-butyl hydroperoxide (TBHP)–mediated oxidative cross-coupling of disulfides with ethers is presented for the synthesis of etherified sulfides. This method is achieved by a C(sp3)-H thiolation strategy under metal-free conditions and provides a simple route to constructing the C-S bonds. GRAPHICAL ABSTRACTKeywords
Funding Information
- We thank the Natural Science Foundation of China (No. 21202121) for financial support.
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