Development of Antiretroviral Drug Resistance
- 18 August 2011
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 365 (7), 637-646
- https://doi.org/10.1056/nejmra1004180
Abstract
Analysis of HIV drug resistance has identified sites on HIV target genes that convey resistance to particular classes of agents. These data may be especially important in designing effective treatment regimens in parts of the world in which non-B subtypes of HIV predominate.Keywords
This publication has 97 references indexed in Scilit:
- Detection of Low-Level K65R Variants in Nucleoside Reverse Transcriptase Inhibitor–Naive Chronic and Acute HIV-1 Subtype C InfectionsThe Journal of Infectious Diseases, 2011
- Distinct Mutation Pathways of Non-Subtype B HIV-1 duringIn VitroResistance Selection with Nonnucleoside Reverse Transcriptase InhibitorsAntimicrobial Agents and Chemotherapy, 2010
- Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada: a population-based studyThe Lancet, 2010
- Longitudinal Analysis of Raltegravir Susceptibility and Integrase Replication Capacity of Human Immunodeficiency Virus Type 1 during Virologic FailureAntimicrobial Agents and Chemotherapy, 2009
- Antiretroviral Drug Resistance in Human Immunodeficiency Virus Type 2Antimicrobial Agents and Chemotherapy, 2009
- The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapyAIDS, 2009
- Emergence of Multiclass Drug–Resistance in HIV‐2 in Antiretroviral‐Treated Individuals in Senegal: Implications for HIV‐2 Treatment in Resouce‐Limited West AfricaClinical Infectious Diseases, 2009
- Prevalence of HIV‐1 Drug Resistance after Failure of a First Highly Active Antiretroviral Therapy Regimen in KwaZulu Natal, South AfricaClinical Infectious Diseases, 2008
- Mutations Associated with Failure of Raltegravir Treatment Affect Integrase Sensitivity to the Inhibitor In VitroAntimicrobial Agents and Chemotherapy, 2008
- Rationale and Uses of a Public HIV Drug‐Resistance DatabaseThe Journal of Infectious Diseases, 2006