A Neural Mass Model to Simulate Different Rhythms in a Cortical Region
Open Access
- 1 December 2009
- journal article
- research article
- Published by Hindawi Limited in Computational Intelligence and Neuroscience
- Vol. 2010, 1-8
- https://doi.org/10.1155/2010/456140
Abstract
An original neural mass model of a cortical region has been used to investigate the origin of EEG rhythms. The model consists of four interconnected neural populations: pyramidal cells, excitatory interneurons and inhibitory interneurons with slow and fast synaptic kinetics, and respectively. A new aspect, not present in previous versions, consists in the inclusion of a self-loop among interneurons. The connectivity parameters among neural populations have been changed in order to reproduce different EEG rhythms. Moreover, two cortical regions have been connected by using different typologies of long range connections. Results show that the model of a single cortical region is able to simulate the occurrence of multiple power spectral density (PSD) peaks; in particular the new inhibitory loop seems to have a critical role in the activation in gamma () band, in agreement with experimental studies. Moreover the effect of different kinds of connections between two regions has been investigated, suggesting that long range connections toward interneurons have a major impact than connections toward pyramidal cells. The model can be of value to gain a deeper insight into mechanisms involved in the generation of rhythms and to provide better understanding of cortical EEG spectra.Keywords
This publication has 12 references indexed in Scilit:
- The Effect of Connectivity on EEG Rhythms, Power Spectral Density and Coherence Among Coupled Neural Populations: Analysis With a Neural Mass ModelIEEE Transactions on Biomedical Engineering, 2007
- Use of a neural mass model for the analysis of effective connectivity among cortical regions based on high resolution EEG recordingsBiological Cybernetics, 2006
- A neural mass model for the simulation of cortical activity estimated from high resolution EEG during cognitive or motor tasksJournal of Neuroscience Methods, 2006
- Networks of interneurons with fast and slow γ-aminobutyric acid type A (GABA A ) kinetics provide substrate for mixed gamma-theta rhythmProceedings of the National Academy of Sciences of the United States of America, 2000
- Brain Rhythms of Language: Nouns Versus VerbsEuropean Journal of Neuroscience, 1996
- Electroencephalogram and visual evoked potential generation in a mathematical model of coupled cortical columnsBiological Cybernetics, 1995
- Synchronized oscillations in interneuron networks driven by metabotropic glutamate receptor activationNature, 1995
- Thalamocortical Oscillations in the Sleeping and Aroused BrainScience, 1993
- Coherent oscillations: A mechanism of feature linking in the visual cortex?Biological Cybernetics, 1988
- Models of Neuronal Populations: The Basic Mechanisms of RhythmicityProgress in Brain Research, 1976