Invasive Pulmonary Aspergillosis Associated with High-Dose Inhaled Fluticasone

Abstract

A 44-year-old man with moderately severe asthma was first seen in the infectious-disease clinic in November 1999 because of a recent diagnosis of pulmonary aspergillosis. The patient had noted an increase in his asthma symptoms during the summer of 1999. A chest x-ray film obtained at that time had revealed bilateral cavitary lesions. An open-lung biopsy in September 1999 had revealed chronic necrotizing aspergillosis.