Studies on scutellariae radix. VI. Effects of flavanone compounds on lipid peroxidation in rat liver.

Abstract
Compounds which inhibited lipid peroxides formation (in in vitro experiments) were isolated together with various flavonoids from the roots of S. baicalensis. From the analytical and physical data, the compounds were identified as (2S)-2'',5,6'',7-tetrahydroxyflavanone (I) and (2R,3R)-2'',3,5,6''7-pentahydroxyflavanone (II), respectively. II inhibited lipid peroxide formation by Fe2+ and ascorbic acid. Both inhibited the lipid peroxide formation induced by ADP and NiADP in rat liver homogenate.