THE ORIGIN OF THE CELLS IN THE EFFERENT LYMPH FROM A SINGLE LYMPH NODE
Open Access
- 1 June 1965
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 121 (6), 901-910
- https://doi.org/10.1084/jem.121.6.901
Abstract
The popliteal nodes of sheep were perfused continuously for over 100 hours with a solution containing (3)H-thymidine. The labelling pattern of the lymphocytes in the efferent lymph from the perfused nodes showed that under normal conditions not more than 4 per cent of these lymphocytes were actually produced in the node. The transitional cells, large lymphocytes and cells of the plasma cell series which appeared in the lymph following antigenic stimulation of the node were all produced in the node.Keywords
This publication has 8 references indexed in Scilit:
- EFFECT OF X-IRRADIATION OF THE POPLITEAL LYMPH-NODE ON ITS OUTPUT OF LYMPHOCYTES AND IMMUNOLOGICAL RESPONSIVENESSThe Lancet, 1964
- The migration of lymphocytes through the endothelium of venules in lymph nodes: an electron microscope studyProceedings of the Royal Society of London. B. Biological Sciences, 1964
- The route of re-circulation of lymphocytes in the ratProceedings of the Royal Society of London. B. Biological Sciences, 1964
- THE LYMPH‐BORNE CELLS OF THE IMMUNE RESPONSEQuarterly Journal of Experimental Physiology and Cognate Medical Sciences, 1963
- Initiation of Immune Responses by Small LymphocytesNature, 1962
- THE OUTPUT OF CELLS IN LYMPH FROM THE POPLITEAL NODE OF SHEEPQuarterly Journal of Experimental Physiology and Cognate Medical Sciences, 1962
- The effect of the continuous re-infusion of lymph and lymphocytes on the output of lymphocytes from the thoracic duct of unanaesthetized rats.1957
- The stripping-film technique of autoradiographyThe International Journal of Applied Radiation and Isotopes, 1956